High-resolution image may be key to treating Zika virus

Researchers have captured the highest-resolution image to date of the Zika virus, which caused a global health crisis in 2015 leaving thousands of babies with serious birth defects. The research team believes the finding may aid in designing a vaccine to fight the virus.

The team used electron microscopy to create a 3D image of Zika, allowing them to visualize the atomic details of the virus. Results were published online June 26 in the journal Structure.

Compared to related viruses such as dengue and yellow fever, Zika is inherently more stable. This new 3D image allowed scientists to identify potential drug-binding pockets on the surface of the virus, which could aid the understanding of how vaccines interact with the virus.

“With the higher resolution, it is now possible to efficiently design vaccines and engineer anti-viral compounds that inhibit the virus," said corresponding author, Michael G. Rossman, a structural biologist at Purdue University in a release.

""

Matt joined Chicago’s TriMed team in 2018 covering all areas of health imaging after two years reporting on the hospital field. He holds a bachelor’s in English from UIC, and enjoys a good cup of coffee and an interesting documentary.

Around the web

CCTA is being utilized more and more for the diagnosis and management of suspected coronary artery disease. An international group of specialists shared their perspective on this ongoing trend.

The new technology shows early potential to make a significant impact on imaging workflows and patient care. 

Richard Heller III, MD, RSNA board member and senior VP of policy at Radiology Partners, offers an overview of policies in Congress that are directly impacting imaging.