Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Contrast protocols based on lean body weight save supplies, reduce patient risk

Adjusting contrast dose based on a patient’s lean body weight provides the same image quality as other administration methods, new data show.

July 16, 2024
With the shortage, which pertains specifically to all formulations and concentrations of GE Healthcare’s Omnipaque (iohexol), expected to last until mid-June, several organizations have eluded that conservation efforts are of critical importance.#contrastshortage #CTcontrast #iodinatedcontrast

The feasibility of reduced contrast flow rates in PE studies

Around one out of every 1,000 people in the U.S. are diagnosed with a pulmonary embolism every year, but even more undergo imaging to rule out clots.  

June 21, 2024

Fluorinated contrast agents show 'strong potential' for MRI theranostics

Experts have developed a first-of-its-kind fluorinated contrast agent they believe will provide more detailed MR imaging and aid in the treatment of certain cancers. 

June 20, 2024

GBCA doses can be reduced by over 50% for some MRI exams

In some cases, contrast doses can be reduced by as much as 62% without sacrificing diagnostic quality.

June 14, 2024
contrast shortage

Dose reduction protocol makes multiple same-day contrast injections possible when necessary

This reduction protocol allows for acceptable lesion visualization while also providing a cautionary cushion when the safety of sequential contrast injections is in question.

May 31, 2024
With the shortage, which pertains specifically to all formulations and concentrations of GE Healthcare’s Omnipaque (iohexol), expected to last until mid-June, several organizations have eluded that conservation efforts are of critical importance.#contrastshortage #CTcontrast #iodinatedcontrast

Investigation into patient's death after contrast injection begins

The man's wife told the court that he had undergone similar scans multiple times before and had never experienced any sort of adverse reaction. 

May 23, 2024
time-delayed MRI phases improve brain tumor visualization

Using multiple MRI phases after contrast injection significantly improves visualization of brain tumors

Researchers are proposing making additional phases beyond the 10-minute mark mandatory when analyzing brain metastases.

May 20, 2024
AI software improves diagnosis of lung conditions when contrast cannot be used

New software could improve diagnosis of lung conditions for patients who cannot tolerate contrast dye

The machine learning-based software uses a formula called the Integrated Jacobian Formulation to calculate lung volume based on metrics derived from imaging taken during inhalation and exhalation. 

May 17, 2024

Around the web

HeartFlow is using SCCT 2024 to introduce the world to its updated Plaque Analysis platform. “Accurately diagnosing a patient’s risk for coronary artery disease is critical for determining the best treatment," Chief Medical Officer Campbell Rogers, MD, explained.

The new images were captured at the European Synchrotron Radiation Facility using hierarchical phase-contrast tomography. One specialist called them "Google Earth for the human heart." 

New data out of England provides cardiologists and radiologists with another reminder of AI's potential to transform healthcare. 

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