Nuclear Medicine

Nuclear medicine (also called molecular imaging) includes positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. Nuclear imaging is achieved by injecting small amounts of radioactive material (radiopharmaceuticals) into patients before or during their scan. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT. But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders.

PET method offers new insight into inflammation of the brain
Researchers are hopeful that their technique could improve the diagnosis of conditions associated with neural inflammation.
New PET imaging method could improve our understanding of long COVID
Researchers have developed a new radiotracer that targets one of the virus’ spike proteins, allowing them to track it longitudinally.
FDA approves new prostate cancer imaging agent with extended shelf life
The new product from Telix paves the way for increased access at clinics where prostate PET may not have been available in the past.
New PET study offers insight into how dopamine drives executive function
These findings could help guide the development of new treatments for psychiatric and neurological disorders.
Bracco updates HeartSee coronary flow capacity software with new diagnostic features
Clinicians have been using HeartSee to diagnose and treat coronary artery disease since the technology first debuted back in 2018. These latest updates, set to roll out to existing users, are designed to improve diagnostic performance and user access.

Some nuc med departments are already feeling the strain of the isotope shortage

"This can't drag on. Patients needing cancer treatment can’t wait two months for an accurate diagnosis.”

NorthStar opens CDMO facility to help develop and distribute radioisotopes.

NorthStar opens facility to assist with development and distribution of vital radioisotopes

The facility will provide much needed developmental and manufacturing support for pharmaceutical companies that produce and distribute medical isotopes.

Georgia Lawrence, JD, with ASNC, explains how CMS uses hospital reported data to develop cardiac PET payment rates.

Understanding hospital billing for cardiac PET/CT

Significant fluctuations in PET and CT reimbursement rates have made it especially challenging to keep up with this complex topic. We spoke to an expert to learn more.

Gila monster saliva helps docs detect insulinomas.

Lizard saliva could be key to spotting elusive pancreatic tumors

By binding the substance to a radiotracer, experts were able to improve the accuracy of identifying these tumors by as much as 30% compared to the standard of care.

New details emerge on looming medical isotope shortage

The supply of Mo-99 and Tc-99m—the most commonly utilized medical isotopes in the world—could be cut by as much as 40% until the reactor in the Netherlands is up and running again.

Warning: Sidelined reactor could trigger medical isotope shortage

The impending shortage pertains to molybdenum-99, or Mo-99. A structural issue has occurred with a pipe within the high-flux reactor in Petten, Netherlands, which will require an immediate repair.

Video of Jamshid Maddahi, MD, UCLA, explaining why flurpiridaz will change cardiac imaging and increase the adoption of PET cardiac imaging.

A closer look at how FDA's flurpiridaz approval will impact nuclear cardiology

The newly approved PET radiotracer is expected to improve patient care significantly. “We have been able to reach the pinnacle of myocardial perfusion imaging with flurpiridaz," one expert said.

Low doses of radiation still increase risk of leukemia, lymphoma and myeloma

A new study found cumulative radiation exposure of 16 mSv to red bone marrow can cause an increased rate of some hematological malignancies.

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