Nuclear Medicine

Nuclear medicine (also called molecular imaging) includes positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. Nuclear imaging is achieved by injecting small amounts of radioactive material (radiopharmaceuticals) into patients before or during their scan. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

Nuclear Regulatory Commission to reconsider extravasation reporting requirements

The NRC noted that advancements in nuclear medicine and increased use of radiopharmaceuticals prompted the commission to reconsider the exclusion of extravasation from medical event reporting.  

January 3, 2023
Cardiac SPECT nuclear imaging myocardial perfusion_Spectrum Dynamics_RSNA22_DF_3.jpeg

ASNC 2023 president calls for nuclear cardiology to embrace new technology

American Society of Nuclear Cardiology (ASNC) 2023 President Mouaz H. Al-Mallah, MD, said the subspecialty needs to up its game with new technology.

January 3, 2023
Regularly eating avocados is associated with a reduced risk of cardiovascular disease, according to a new study.

Why clinicians should know if patients are on the keto diet before undergoing PET imaging

Patients adhering to a ketogenic diet can show reduced cerebral 18F-FDG uptake on PET imaging, study shows.

December 21, 2022

CMS cites 'newly published evidence' in postponement of PET coverage decision

Prior to the Dec. 15 announcement, CMS had released a different statement in June informing the public that they were reconsidering the amount of PET scans that Alzheimer’s patients undergoing monoclonal antibody treatment can receive.

December 19, 2022
A CT coronary calcium scoring exam at Northwestern Medicine's Central DuPage Hospital in the Chicago Suburbs. Dave Fornell

Trends in the number of radiology studies and a decline in radiation dose

A special report in Radiology offers a rare overview of the number of radiology exams performed each year worldwide and focuses on the decline of associated radiation doses patients receive.

December 19, 2022
The GE Starguide SPECT-CT system on display at RSNA 2022.

SPECT technique might measure absorbed tissue dose from radiation therapy

Washington University is using a novel low-count quantitative SPECT technique to measure the concentration of alpha particle radiopharmaceutical therapy activity in the tumor and in radio-sensitive organs.
 

December 16, 2022

New radiotracer IDs numerous cancers likely to respond to targeted therapy

The radiotracer, 68Ga-PentixaFor, can be used for detecting C-X-C motif chemokine receptor 4 (CXCR4), which plays a significant role in cancer progression.

December 8, 2022
An example of a positive amyloid plaque PET nuclear brain scan. these tests can help identify Alzheimer's patients earlier so they can be prescribed drugs to treat the condition.

Cognitive decline not far behind amyloid and tau PET-positive scans, even for the asymptomatic

Common markers of Alzheimer's disease visualized on PET scans of asymptomatic patients might foreshadow the onset of symptoms in the years following their initial discovery.

December 7, 2022

Around the web

The newly approved AI models are designed to improve the detection of pulmonary embolisms and strokes in patients who undergo CT scans.

"I see, at least for the next decade, this being a SPECT and PET world, not one or the other," explained Tim Bateman, MD.

The FDA-approved technology developed by HeartFlow can predict a patient's long-term risk of target vessel failure as well as more invasive treatments performed inside a cath lab. 

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