Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

A comparison between a traditional iodine contrast angiogram (left), and a gadolinium contrast angiogram (right). MRI gadolinium contrast is starting to be used in some interventional radiology procedures and is being considered in interventional cardiology due to the iodine contrast shortage.

Gadolinium can be used as substitute for iodine contrast in some interventional imaging procedures

Gadolinium might be an alternative, stop-gap solution for interventional procedures during the current iodine contrast shortage.

The imaging iodine contrast shortage is delaying procedures and causing rationing at hospitals. impact is it having on hospitals and the tough decisions that are being made to triage patients to determine if they will get a contrast CT scan or an interventional or surgical procedure requiring contrast. Photo by Dave Fornell

VIDEO: Imaging contrast shortage is delaying procedures and causing rationing

Alan H. Matsumoto, MD, chair of the department of radiology at the University of Virginia and vice chair of the American College of Radiology Board of Chancellors, explains the contrast shortage situation and the tough decisions providers are being forced to make.

Alan Matsumoto explains gadolinium as substitute for iodine contrast during shortage

VIDEO: Gadolinium being substituted for iodine contrast in some procedures due to shortage

Alan H. Matsumoto, MD, chair of the department of radiology at the University of Virginia, vice chair of the American College of Radiology (ACR) Board of Chancellors, and chairman of the ACR Commission on Interventional and Cardiovascular Radiology, explains that the iodine contrast shortage has led to use of MRI gadolinium contrast agents in some cases.

Kirk Garratt, past SCAI president, explains the impact of the iodine contrast shortage on interventional cardiology and the cath lab. #SCAI

VIDEO: How the iodine contrast shortage is impacting interventional cath labs

Kirk Garratt, MD, medical director of the Center for Heart and Vascular Health, ChristianaCare, and a past president of SCAI, explains what this shortage means for interventional cardiologists.

Addressing contrast media shortage in the short, mid and long term

“We need to commit to changing the supply chain so that a single event in a faraway country does not put us in this predicament again," experts wrote in a new special report shared by Radiology.

GE provides update on contrast media shortage

The COVID lockdowns at the Shanghai plant began on March 31, and although the plant there has since resumed operations, they are not yet at 100% capacity.

Preserving contrast media supplies: 7 ACR recommendations

With the shortage, which pertains specifically to all formulations and concentrations of GE Healthcare’s Omnipaque (iohexol), expected to last until mid-June, several organizations have alluded that conservation efforts are of critical importance.

Be prepared: IV contrast media shortage could last up to 8 weeks

All formulations and concentrations of GE Healthcare’s Omnipaque (iohexol) are expected to be in short supply until mid-June due to COVID lockdowns where the contrast is manufactured.

Around the web

The nuclear imaging isotope shortage of molybdenum-99 may be over now that the sidelined reactor is restarting. ASNC's president says PET and new SPECT technologies helped cardiac imaging labs better weather the storm.

CMS has more than doubled the CCTA payment rate from $175 to $357.13. The move, expected to have a significant impact on the utilization of cardiac CT, received immediate praise from imaging specialists.

The newly cleared offering, AutoChamber, was designed with opportunistic screening in mind. It can evaluate many different kinds of CT images, including those originally gathered to screen patients for lung cancer. 

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