Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography, RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

Experts may have discovered why some patients are more susceptible to GBCA-related side effects
A new study focuses on the role oxalic acid may play in the body’s ability to eliminate gadolinium after an MRI study.
Right heart cardiac ultrasound contrast agent for shunts enters U.S. trial
Currently there are no FDA cleared echocardiography contrast agents commercially available for use on the right side of the heart to detect shunts, but a new agent that promises to improve workflow and imaging is about to enter a U.S. trial.
Why researchers believe silver nanoparticles could 'revolutionize' medical imaging
Researchers at Oregon State University are working on developing a way to make contrast agents more targeted.
Many CT techs unprepared to manage adverse contrast reactions
Though rare, some reactions can be life-threatening, making the understanding of how to appropriately manage them a critical aspect of a technologist's responsibilities.
GE Healthcare investing $138 million to bolster contrast supply
It is estimated that the demand for contrast-enhanced imaging could double over the next decade.

New data suggest clinicians should think twice before foregoing contrast-enhanced imaging

The new data highlight a potential pitfall of unenhanced CT scans on patients presenting to emergency departments with acute pain—an inaccurate workup.

ACR applauds FDA about-face on use of iodinated contrast in children

The update marks a change from the FDA's stance on the topic last year.

CCTA with patient-specific versus fixed post-trigger delay

Patient-specific versus fixed post-trigger delay: Which offers superior CCTA image quality?

New research compares peak enhancement timing of a patient-specific post-trigger delay and a fixed delay during CCTA.

Iodine contrast being loaded into a contrast injector in preparation for a cardiac CT scan at Duly Health and Care in Lisle, Illinois. The contrast shortage is causing some healthcare organizations to postpone exams and procedures and ration contrast supplies. Photo by Dave Fornell

How to manage patients in need of contrast-enhanced imaging following an allergic-like reaction

Up to one-third or more of patients who experience moderate or severe allergic-like reactions to ICM must have their imaging protocols revised when subsequent exams involving contrast are requested.

GBCA dose drops significantly in breast MRI thanks to machine learning

The use of synthetic images could reduce the amount of gadolinium-based contrast agents needed for breast MRI examinations, according to new data published this week in Radiology.

GE HealthCare's new MRI contrast agent advances to clinical trial

Experts are hopeful that the first-of-its-kind injectable manganese-based macrocyclic agent will offer a suitable alternative to GBCAs, as it can be more efficiently eliminated from the body.

Expert left 'astounded' by gadolinium discovery

New data out of the University of New Mexico suggest that the imaging agent’s physiologic reach may exceed what was previously believed.

New contrast agent is officially available for use in hospitals and clinics

A Feb. 14 announcement from Bracco indicates that the recently FDA-approved, gadolinium-based contrast agent VUEWAY, also known as gadopiclenol, is officially being used for patients undergoing MR imaging.

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Right heart cardiac ultrasound contrast agent for shunts enters U.S. trial

Currently there are no FDA cleared echocardiography contrast agents commercially available for use on the right side of the heart to detect shunts, but a new agent that promises to improve workflow and imaging is about to enter a U.S. trial.