Molecular Imaging

Molecular imaging (also called nuclear medicine or nuclear imaging) can image the function of cells inside the body at the molecular level. This includes the imaging modalities of positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. How does PET and SPECT imaging work? Small amounts of radioactive material (radiopharmaceuticals) injected into a patient. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

New PET imaging approach depicts widespread damage of early Alzheimer’s

A novel radiotracer and synaptic imaging revealed "widespread" losses throughout the brain, Yale University researchers reported Wednesday.

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Australian reactor produces new radioisotope with potential to enhance molecular imaging

The Australian Nuclear Science and Technology Organization said its new scandium-47 radioisotope has applications in both PET and SPECT approaches.

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Digital PET/CT roots out smaller cancers with quicker imaging times

Clinicians using this modern machine can get a more accurate contrast measurement and improve their cancer diagnosis, researchers wrote in the Journal of Nuclear Medicine.

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PSMA PET/CT tops conventional imaging for pinpointing high-risk cancer

Australian researchers also recommended updating current diagnostic pathways to incorporate the new molecular imaging approach.

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Medical imaging radiation exposure fell by 20% over past decade

The drop bucks a nearly quarter-century-long trend in rising radiation dosage, dating back to 1980, researchers wrote Tuesday in Radiology.

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ASNC monitoring potential Mo-99 supply shortages due to COVID-19

The president of the American Society of Nuclear Cardiology said there are no shortfalls reported at this time, but the organization is keeping an eye on the situation as more countries implement travel bans.

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Simple sit-down has outsized impact on patients prepping for nuclear medicine exams

Montefiore Medical Center has been running its pretreatment nuclear medicine clinic for 14 years, and its had an overwhelming impact on patients, according to a new study published in Current Problems in Diagnostic Radiology.

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NorthStar expands into cardiac SPECT with new licensing deal

The Beloit, Wisconsin-based company has received exclusive rights from Capella Imaging to develop and investigate a new fibrin-targeted diagnostic agent that's used in heart imaging exams.

Around the web

Positron, a New York-based nuclear imaging company, will now provide Upbeat Cardiology Solutions with advanced PET/CT systems and services. 

The nuclear imaging isotope shortage of molybdenum-99 may be over now that the sidelined reactor is restarting. ASNC's president says PET and new SPECT technologies helped cardiac imaging labs better weather the storm.

CMS has more than doubled the CCTA payment rate from $175 to $357.13. The move, expected to have a significant impact on the utilization of cardiac CT, received immediate praise from imaging specialists.

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