Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

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GBCA doses can be reduced by over 50% for some MRI exams

In some cases, contrast doses can be reduced by as much as 62% without sacrificing diagnostic quality.

Dose reduction protocol makes multiple same-day contrast injections possible when necessary

This reduction protocol allows for acceptable lesion visualization while also providing a cautionary cushion when the safety of sequential contrast injections is in question.

Investigation into patient's death after contrast injection begins

The man's wife told the court that he had undergone similar scans multiple times before and had never experienced any sort of adverse reaction. 

time-delayed MRI phases improve brain tumor visualization

Using multiple MRI phases after contrast injection significantly improves visualization of brain tumors

Researchers are proposing making additional phases beyond the 10-minute mark mandatory when analyzing brain metastases.

AI software improves diagnosis of lung conditions when contrast cannot be used

New software could improve diagnosis of lung conditions for patients who cannot tolerate contrast dye

The machine learning-based software uses a formula called the Integrated Jacobian Formulation to calculate lung volume based on metrics derived from imaging taken during inhalation and exhalation. 

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One adverse reaction to a GBCA significantly increases risk of another in the future

The type of gadolinium-based agent administered could also increase the risk of reaction, a new study suggests.

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Could diamond dust replace gadolinium in MRI contrast agents?

An accidental discovery could have future implications for the material makeup for MRI contrast media.

The imaging iodine contrast shortage is delaying procedures and causing rationing at hospitals. impact is it having on hospitals and the tough decisions that are being made to triage patients to determine if they will get a contrast CT scan or an interventional or surgical procedure requiring contrast. Photo by Dave Fornell

ChatGPT shows 'significant promise' in guiding contrast-related decisions

This could be especially helpful when timely clinical decisions relative to the use of a contrast agent need to be made.

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