Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

MRA for pulmonary embolus

MR angiography a suitable alternative to CT when ruling out pulmonary embolus

The modality switch became especially important during the iodinated contrast shortage of 2022 when clinics were forced to deploy mitigation tactics as a means of preserving their contrast supply. 

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When GBCA use in musculoskeletal imaging is and is not appropriate

Although gadolinium-based contrast agents are largely considered safe and are routinely used for MRI exams, experts suggest that providers should still utilize GBCAs sparingly for musculoskeletal studies.

Philips' latest collaboration could make xenon MR imaging more widely available

In alliance with Polarean, Philips is rolling out a new MR system with advanced multi-nuclei imaging capabilities that will offer radiologists a detailed evaluation of lung ventilation using xenon gas as a contrast agent.

Is warming iodinated contrast prior to use really necessary?

The ACR Manual on Contrast Media suggests that highly viscous ICM should be warmed to body temperature prior to administration when using high-rate intravenous low-osmolality power injections, viscous iodinated CM, small-caliber catheters, or for timed studies looking at peak enhancement.   

The new MRI contrast agent gadopiclenol, sold under the trade names Elucirem and Vueway by Bracco and Guerbet, used 50% less gadolinium that current MRI agents. #RSNA22 #RSNA

New contrast agent earns positive safety classification from ACR

The ACR Committee on Drugs and Contrast Media stated that exposure to the gadolinium-based contrast agent represents a “sufficiently low or possibly nonexistent” risk to patients.

New data suggest clinicians should think twice before foregoing contrast-enhanced imaging

The new data highlight a potential pitfall of unenhanced CT scans on patients presenting to emergency departments with acute pain—an inaccurate workup.

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ACR applauds FDA about-face on use of iodinated contrast in children

The update marks a change from the FDA's stance on the topic last year.

CCTA with patient-specific versus fixed post-trigger delay

Patient-specific versus fixed post-trigger delay: Which offers superior CCTA image quality?

New research compares peak enhancement timing of a patient-specific post-trigger delay and a fixed delay during CCTA.

Around the web

The nuclear imaging isotope shortage of molybdenum-99 may be over now that the sidelined reactor is restarting. ASNC's president says PET and new SPECT technologies helped cardiac imaging labs better weather the storm.

CMS has more than doubled the CCTA payment rate from $175 to $357.13. The move, expected to have a significant impact on the utilization of cardiac CT, received immediate praise from imaging specialists.

The newly cleared offering, AutoChamber, was designed with opportunistic screening in mind. It can evaluate many different kinds of CT images, including those originally gathered to screen patients for lung cancer. 

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