Imaging Contrast

Contrast agents are injected into patients to help enhance images to make it easier for radiologists distinguish specific areas of the body from surrounding tissues. The most commonly used agents are iodinated contrast dye for computed tomography (CT), interventional cath lab angiography,  RF fluoroscopy, and in surgical OR procedures. MRI scans typically use gadolinium-based contrast agents. Ultrasound and echocardiography (cardiac ultrasound) imaging use contrast agents composed of microscopic bubbles to enhance images that otherwise would be suboptimal.

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How the 2022 contrast media shortage impacted stroke care

A team of specialists tracked CT utilization before, during and after the 2022 shortage, sharing its findings in the American Journal of Neuroradiology.

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Generic substitute for gadolinium-based contrast agent Gadavist hits the market

The contrast agent, simply called Gadobutrol Injection, has been approved by the U.S. Food and Drug Administration and is now available in the United States.

Rethinking ICM storage could help imaging departments reduce waste by 59%

“While drug pricing is not opaque and absolute costs of medications can vary widely, any waste comes at a cost," researchers wrote in a new analysis. 

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PROMISE trial results reinforce confidence in new MRI contrast agent

The randomized, double-blinded phase 3 study revealed gadopiclenol to be noninferior to gadobutrol for all qualitative visualization parameters as rated by all blinded readers involved in the trial.

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New discovery paves the way for copper's entrance into MRI contrast agents

The new discovery contradicts the notion that copper is not suitable for use in contrast media.

Syringeless contrast media injectors like the GE Ulrich CT Motion have gained a lot of interest in 2022 because of the iodine contrast shortage. These systems use rollers to squeeze precise amounts of contrast from a large bolus container for multiple patients, helping conserve a significant amount of contrast.

Multi-use syringeless injectors could completely eliminate contrast waste

Such products could increase departmental efficiency and advance environmental initiatives in radiology, experts claimed in Academic Radiology.

MRA for pulmonary embolus

MR angiography a suitable alternative to CT when ruling out pulmonary embolus

The modality switch became especially important during the iodinated contrast shortage of 2022 when clinics were forced to deploy mitigation tactics as a means of preserving their contrast supply. 

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When GBCA use in musculoskeletal imaging is and is not appropriate

Although gadolinium-based contrast agents are largely considered safe and are routinely used for MRI exams, experts suggest that providers should still utilize GBCAs sparingly for musculoskeletal studies.

Around the web

The newly approved PET radiotracer is expected to improve patient care significantly. “We have been able to reach the pinnacle of myocardial perfusion imaging with flurpiridaz," one expert said.

GE HealthCare's flurpiridaz, the PET radiotracer that recently received FDA approval, offers several key benefits over SPECT. Jamshid Maddahi, MD, discussed the details in an exclusive interview. 

Ultrafast MCE could go on to become a go-to treatment option for obstructive coronary artery disease, according to the authors of a new first-in-human clinical study.

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